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Datasets and Documentation

Exam 1 Datasets

This page contains data sets and documentation for Exam 1. Specifically, clinic data for all of the 6814 enrolled MESA participants are available. Data was originally posted May 13, 2003 and May 19, 2003. Please see dates listed next to each file. 

The data documentation herein contain descriptions of all variables included in the main and Reading Center data sets, including created variables. 

Reading Center (RC) data are also included for a subset of these enrollees depending on the receipt and availability of clean data at the CC. Data sets are provided in SPSS, SAS and STATA formats. In particular, the following data files are contained within the .zip links for each format:

  • Main file: This file includes variables from clinic procedures and questionnaires, created analytic variables (e.g. body mass index), and key RC variables (e.g. average total calcium score).
  • Reading Center (RC) files: A separate data file is provided for each RC that contains all the RC variables collected. The following RC data sets are included: ECG, CT, MRI, IMT, Distensibility, Blood, and Urine. Note that the CT files contain multiple (up to two) scans per enrollee.
Datasets having an associated investigator name are either complex, specialized data or ancillary study datasets that are now available to all MESA investigators. It is recommended that those making use of these datasets collaborate with the associated investigator.

Data Documentation

Review of documentation prior to initiating analyses is strongly recommended. Please refer to the MESA Data Analysis Recommendations located here.

Documentation File Posted
All Exam and Ancillary Study Assay Inventory March 7, 2025
De-Identified Data Distribution Policy April 14, 2016
Exam 1 Data Updates completed October 25, 2024
Exam 1 Main Final Label Data Set Variable Guide March 7, 2024
Information for New Investigators October 19, 2022
Omics summary documentation October 25, 2024
DD: Aortic Valvular Calcium July 19, 2006
DD: Aortic Valvular Calcium (Exams 1 - 3) July 13, 2023
DD: Apolipoprotein E (Isoform) February 11, 2013
DD: Apolipoprotein E (recommended) March 11, 2014
DD: Blood Group 1 / 2 / 3 Assay Methods August 5, 2014
DD: Blood Group 2 May 3, 2013
DD: Blood Group 4 Assay November 9, 2010
DD: Cardiac CT January 11, 2013
DD: Cardiac MRI July 7, 2014
DD: Cardiac MRI Completion Status November 27, 2012
DD: Cardiac MRI QC January 18, 2013
DD: Consent Status by Field Center February 25, 2005
DD: Created Variables documentation October 11, 2016
DD: Diet and Nutrients documentation December 8, 2015
DD: Diet Correction Documentation July 10, 2015
DD: DNA Extraction Methods July 10, 2012
DD: ECG codes September 5, 2014
DD: ECG Continuous Waveform September 5, 2014
DD: Imputed Blood Pressure February 24, 2014
DD: Imputed Cholesterol February 24, 2014
DD: Less Used Data October 1, 2004
DD: Medication Variable Definitions January 5, 2015
DD: MESA FMD January 9, 2009
DD: Pulse Wave March 25, 2005
DD: Pulse Wave PPA May 2, 2017
DD: Pulse Wave Summary Measure June 12, 2007
DD: Ultrasound IMT Combined Wisconsin Re-Read October 10, 2016
DD: Ultrasound IMT Distensibility July 28, 2023
DD: Ultrasound IMT documentation March 30, 2010
DD: Ultrasound IMT Gray Scale Median Plaque February 9, 2017
Combined SPSS, SAS and STATA files (.zip)
Dataset Posted
Main Exam 1 Final Label Dataset
March 7, 2024
Omics Summary
October 25, 2024
Aortic Valvular Calcium (Exams 1, 2, and 3)
July 13, 2023
Apolipoprotein E (Recommended and Isoform)
November 17, 2015
Blood Group 2, 3, and 4
November 20, 2015
Cardiac CT
October 22, 2014
Cardiac CT Alert
February 10, 2016
Cardiac MRI, Re-Read, Completion Status
November 17, 2015
ECG Code and Continuous Waveform
September 5, 2014
ECG Ectopic Beat
October 9, 2024
ECG QRST Angles
October 9, 2024
Flow-Mediated Dilation (FMD)
January 9, 2009
Imputed BP
February 24, 2014
Imputed Cholesterol
February 24, 2014
NMR Lipids LP2 and LP3
November 20, 2015
Physical Activity
November 20, 2015
Pulse Wave Summary, PPA, and Post
February 25, 2019
Sphyngomyelin
May 16, 2008
Ultrasound IMT and Distensibility
July 28, 2023
Ultrasound IMT Combined Wisconsin Re-Read
October 10, 2016
Ultrasound IMT Gray Scale Median Plaque
February 9, 2017
Urinary Albumin QC
January 28, 2010